Complement Inhibition Alleviates Cholestatic Liver Injury Through Mediating Macrophage Infiltration and Function in Mice

Complement Inhibition Alleviates Cholestatic Liver Injury Through Mediating Macrophage Infiltration and Function in Mice

Background and AimsCholestatic liver injury (CLI), which is associated with inflammatory reactions and oxidative stress, is a serious risk factor for postoperative complications. Complement system is involved in a wide range of liver disorders, including cholestasis. The present study assessed the r...

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Bibliographic Details
Main Authors: Zhenya Guo, Junze Chen, Yonglian Zeng, Zefeng Wang, Mei Yao, Stephen Tomlinson, Bin Chen, Guandou Yuan, Songqing He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
cholestatic liver injury
complement system
CR2-Crry
neutrophil
macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.785287/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.785287/full

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