Multiparametric flow cytometry directing the evaluation of CRLF2 rearrangements and JAK2 status in pediatric B cell precursor acute lymphoblastic leukemia

Asbtract: Introduction: This study aimed to determine whether cytokine receptor-like factor 2 (CRLF2) antigen expression evaluated using multiparametric flow cytometry (MFC) could predict the genotype of CRLF2 and Janus kinase 2 (JAK2) status for application in the diagnosis of pediatric B-cell pre...

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Main Authors: Elda Pereira Noronha, Priscilla Moniz Sodré Ferreira, Francianne Gomes Andrade, Caroline Barbieri Blunck, Ricardo Camargo, Etel Rodrigues Pereira Gimba, Maria S. Pombo-de-Oliveira, Eugênia Terra-Granado
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Hematology, Transfusion and Cell Therapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S2531137922000980