Lipopolysaccharide Exposure Differentially Alters Plasma and Brain Inflammatory Markers in Adult Male and Female Rats

Humans and rodents have sexually dimorphic immune responses, which could influence the brain’s response to a systemic inflammatory insult. Lipopolysaccharide (LPS) is a stimulator of the innate immune system and is routinely used in animal models to study blood–brain barrier (BBB) dysfunction under...

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Bibliographic Details
Main Authors: Hannah A. Nonoguchi, Timothy Wee Shang Kouo, Sandhya Kortagere, Joshua Hillman, David L. Boyle, Chitra D. Mandyam
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/12/8/972