Assessment of weighted topological overlap (wTO) to improve fidelity of gene co-expression networks

Assessment of weighted topological overlap (wTO) to improve fidelity of gene co-expression networks

Abstract Background For more than a decade, gene expression data sets have been used as basis for the construction of co-expression networks used in systems biology investigations, leading to many important discoveries in a wide range of subjects spanning human disease to evolution and the developme...

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Bibliographic Details
Main Authors: André Voigt, Eivind Almaas
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Bioinformatics
Subjects:
Gene co-expression network
Weighted topological overlap
Correlation network
Biological network analysis
Online Access:http://link.springer.com/article/10.1186/s12859-019-2596-9

Internet

http://link.springer.com/article/10.1186/s12859-019-2596-9

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