MK-801 changes the expression of mBDNF and proBDNF in the hippocampus of rats with corticosterone-induced depression-like behavior

Objective N-methyl-D-aspartate (NMDA) receptor antagonist produces antidepressant effects through the brain-derived neurotrophic factor (BDNF). However, the mechanism of NMDA regulation of BDNF expression by receptor antagonist is unclear. Methods Corticosterone (CORT) was orally administrated t...

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Bibliographic Details
Main Author: LI Jian-guo, WANG Ying, LI Yue-tian, YAN Zi, ZHAO Xin, ZHANG Yu
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2021-08-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a201324.pdf