CD8CD28 T Cells: A Human CD8 T-Suppressor Subpopulation with Alloantigen Specificity Induced by Soluble HLA-A2 Dimer in Vitro

CD8CD28 T Cells: A Human CD8 T-Suppressor Subpopulation with Alloantigen Specificity Induced by Soluble HLA-A2 Dimer in Vitro

CD8 + suppressor T cells have been demonstrated to provide protection of allografts from rejection. We previously reported that soluble peptide/HLA-A2 dimer shows peptide-specific inhibitory effects on alloresponse in a coculture of peptide-pulsed T2 cells with HLA-A2 negative lymphocytes in vitro....

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Bibliographic Details
Main Authors: Zhigang Wang, Lichen Ouyang, Zhihui Liang, Jun Chen, Qian Yu, Victor Tunje Jeza, Yeli Gong, Guanxin Shen, Xiufang Weng, Xiongwen Wu
Format: Article
Language:English
Published: SAGE Publishing 2015-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368914X683575

Internet

https://doi.org/10.3727/096368914X683575

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