von Willebrand Factor: A Central Regulator of Arteriovenous Fistula Maturation Through Smooth Muscle Cell Proliferation and Outward Remodeling

Background Arteriovenous fistula (AVF) maturation failure is a main limitation of vascular access. Maturation is determined by the intricate balance between outward remodeling and intimal hyperplasia, whereby endothelial cell dysfunction, platelet aggregation, and vascular smooth muscle cell (VSMC)...

Full description

Bibliographic Details
Main Authors: Suzanne L. Laboyrie, Margreet R. de Vries, Alwin de Jong, Hetty C. de Boer, Reshma A. Lalai, Laisel Martinez, Roberto I. Vazquez‐Padron, Joris I. Rotmans
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.024581