Discovery of Novel Mono-Carbonyl Curcumin Derivatives as Potential Anti-Hepatoma Agents

Curcumin possesses a wide spectrum of liver cancer inhibition effects, yet it has chemical instability and poor metabolic properties as a drug candidate. To alleviate these problems, a series of new mono-carbonyl curcumin derivatives <b>G1–G7</b> were designed, synthesized, and evaluated...

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Bibliographic Details
Main Authors: Weiya Cao, Pan Yu, Shilong Yang, Zheyu Li, Qixuan Zhang, Zengge Liu, Hongzhuo Li
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/19/6796