Non-Invasive Iontophoretic Delivery of Cytochrome c to the Posterior Segment and Determination of Its Ocular Biodistribution

Non-Invasive Iontophoretic Delivery of Cytochrome c to the Posterior Segment and Determination of Its Ocular Biodistribution

The intact porcine eye globe model was used to demonstrate that transscleral iontophoresis could deliver a small protein, cytochrome c (Cyt c), to the posterior segment and to investigate post-iontophoretic biodistribution in the different ocular compartments. The effects of Cyt c concentration (1,...

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Bibliographic Details
Main Authors: Laura Gisela González Iglesias, Siwar Messaoudi, Yogeshvar N. Kalia
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
transscleral iontophoresis
cytochrome c
non-invasive ocular delivery
macromolecule
posterior segment drug delivery
Online Access:https://www.mdpi.com/1999-4923/14/9/1832

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https://www.mdpi.com/1999-4923/14/9/1832

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