Antibiotic selection pressure and macrolide resistance in nasopharyngeal Streptococcus pneumoniae: a cluster-randomized clinical trial.

Antibiotic selection pressure and macrolide resistance in nasopharyngeal Streptococcus pneumoniae: a cluster-randomized clinical trial.

It is widely thought that widespread antibiotic use selects for community antibiotic resistance, though this has been difficult to prove in the setting of a community-randomized clinical trial. In this study, we used a randomized clinical trial design to assess whether macrolide resistance was highe...

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Bibliographic Details
Main Authors: Alison H Skalet, Vicky Cevallos, Berhan Ayele, Teshome Gebre, Zhaoxia Zhou, James H Jorgensen, Mulat Zerihun, Dereje Habte, Yared Assefa, Paul M Emerson, Bruce D Gaynor, Travis C Porco, Thomas M Lietman, Jeremy D Keenan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC3001893?pdf=render

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http://europepmc.org/articles/PMC3001893?pdf=render

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