Multicellular Tumor Spheroids as an in Vivo–Like Tumor Model for Three-Dimensional Imaging of Chemotherapeutic and Nano Material Cellular Penetration

Multicellular Tumor Spheroids as an in Vivo–Like Tumor Model for Three-Dimensional Imaging of Chemotherapeutic and Nano Material Cellular Penetration

We present a flexible and highly reproducible method using three-dimensional (3D) multicellular tumor spheroids to quantify chemotherapeutic and nanoparticle penetration properties in vitro. We generated HeLa cell–derived spheroids using the liquid overlay method. To properly characterize HeLa spher...

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Detalles Bibliográficos
Main Authors: Hui-li Ma, Qiao Jiang, Siyuan Han, Yan Wu, Jin Cui Tomshine, Dongliang Wang, Yaling Gan, Guozhang Zou, Xing-Jie Liang
Formato: Artigo
Idioma:English
Publicado: SAGE Publishing 2012-11-01
Series:Molecular Imaging
Acceso en liña:https://doi.org/10.2310/7290.2012.00012

Internet

https://doi.org/10.2310/7290.2012.00012

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