How to study runs of homozygosity using PLINK? A guide for analyzing medium density SNP data in livestock and pet species

How to study runs of homozygosity using PLINK? A guide for analyzing medium density SNP data in livestock and pet species

Abstract Background PLINK is probably the most used program for analyzing SNP genotypes and runs of homozygosity (ROH), both in human and in animal populations. The last decade, ROH analyses have become the state-of-the-art method for inbreeding assessment. In PLINK, the --homozyg function is used t...

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Bibliographic Details
Main Authors: R. Meyermans, W. Gorssen, N. Buys, S. Janssens
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Genomics
Subjects:
PLINK
Runs of homozygosity
Minor allele frequency
Linkage disequilibrium
SNP density
Online Access:https://doi.org/10.1186/s12864-020-6463-x

Internet

https://doi.org/10.1186/s12864-020-6463-x

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