Identification of a distal enhancer of Ucp1 essential for thermogenesis and mitochondrial function in brown fat
Abstract Uncoupling protein 1 (UCP1) is a crucial protein located in the mitochondrial inner membrane that mediates nonshivering thermogenesis. However, the molecular mechanisms by which enhancer–promoter chromatin interactions control Ucp1 transcriptional regulation in brown adipose tissue (BAT) ar...
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Nature Portfolio
2025-01-01
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| श्रृंखला: | Communications Biology |
| ऑनलाइन पहुंच: | https://doi.org/10.1038/s42003-025-07468-3 |