Whole-exome sequencing and bioinformatic analyses revealed differences in gene mutation profiles in papillary thyroid cancer patients with and without benign thyroid goitre background

Whole-exome sequencing and bioinformatic analyses revealed differences in gene mutation profiles in papillary thyroid cancer patients with and without benign thyroid goitre background

BackgroundPapillary thyroid cancer (PTC) is the most common thyroid malignancy. Concurrent presence of cytomorphological benign thyroid goitre (BTG) and PTC lesion is often detected. Aberrant protein profiles were previously reported in patients with and without BTG cytomorphological background. Thi...

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Bibliographic Details
Main Authors: Zing Hong Eng, Mardiaty Iryani Abdullah, Khoon Leong Ng, Azlina Abdul Aziz, Nurul Hannis Arba’ie, Nurullainy Mat Rashid, Sarni Mat Junit
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Endocrinology
Subjects:
benign thyroid goitre
whole-exome sequencing
thyroid tumourigenesis
single nucleotide variants
papillary thyroid cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1039494/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.1039494/full

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