Soluble CD163 is produced by monocyte-derived and alveolar macrophages, and is not associated with the severity of idiopathic pulmonary fibrosis
The soluble form of the membrane hemoglobin scavenger receptor CD163 (sCD163), released by shedding, is a strong marker for macrophage activation. Serum sCD163 levels rise in several acute inflammatory states and some fibrosing diseases. Monocyte-derived macrophages (MoDM) differentiated by macropha...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2022-04-01
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Series: | Innate Immunity |
Online Access: | https://doi.org/10.1177/17534259221097835 |