A high-throughput assay for directly monitoring nucleolar rRNA biogenesis

Studies of the regulation of nucleolar function are critical for ascertaining clearer insights into the basic biological underpinnings of ribosome biogenesis (RB), and for future development of therapeutics to treat cancer and ribosomopathies. A number of high-throughput primary assays based on morp...

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Bibliographic Details
Main Authors: Carson J. Bryant, Mason A. McCool, Laura Abriola, Yulia V. Surovtseva, Susan J. Baserga
Format: Article
Language:English
Published: The Royal Society 2022-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.210305