Apolipoprotein E Protects against NMDA Excitotoxicity

Apolipoprotein E Protects against NMDA Excitotoxicity

Preclinical and clinical evidence implicates a role for endogenous apolipoprotein E in modifying the response of the brain to focal and global ischemia. To investigate whether apoE modulates the neuronal response to glutamate excitotoxicity, we exposed primary neuronal glial cultures and a neuronal...

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Bibliographic Details
Main Authors: Mitsuo Aono, Yoonki Lee, Elfrida R. Grant, Robert A. Zivin, Robert D. Pearlstein, David S. Warner, Ellen R. Bennett, Daniel T. Laskowitz
Format: Article
Language:English
Published: Elsevier 2002-10-01
Series:Neurobiology of Disease
Subjects:
excitotoxicity
NMDA
apolipoprotein E
cell culture
calcium influx
neuroprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996102905413

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http://www.sciencedirect.com/science/article/pii/S0969996102905413

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