Hypoxia induces hepatocellular carcinoma metastasis via the HIF-1α/METTL16/lnc-CSMD1-7/RBFOX2 axis

Hypoxia induces hepatocellular carcinoma metastasis via the HIF-1α/METTL16/lnc-CSMD1-7/RBFOX2 axis

Summary: Hypoxic microenvironment is clinically associated with metastasis and poor prognosis of numerous cancers. The mechanisms by which intratumoral hypoxia regulates metastasis are not fully understood. Our study identifies a downregulation of Lnc-CSMD1-7 in hepatocellular carcinoma (HCC) and co...

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Bibliographic Details
Main Authors: Yingchao Wang, Yong Yang, Ye Yang, Yuan Dang, Zhiting Guo, Qiuyu Zhuang, Xiaoyuan Zheng, Fei Wang, Niangmei Cheng, Xiaolong Liu, Wuhua Guo, Bixing Zhao
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Molecular biology
Epigenetics
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223025725

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http://www.sciencedirect.com/science/article/pii/S2589004223025725

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