Fast and efficient copper-mediated 18F-fluorination of arylstannanes, aryl boronic acids, and aryl boronic esters without azeotropic drying

Fast and efficient copper-mediated 18F-fluorination of arylstannanes, aryl boronic acids, and aryl boronic esters without azeotropic drying

Abstract Background Copper-mediated radiofluorination is a straightforward method to produce a variety of [18F]fluoroarenes and [18F]fluoroheteroarenes. To minimize the number of steps in the production of 18F-labelled radiopharmaceuticals, we have developed a short and efficient azeotropic drying-f...

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Bibliographic Details
Main Authors: Salla Orvokki Lahdenpohja, Noora Annika Rajala, Johan Rajander, Anna Kaarina Kirjavainen
Format: Article
Language:English
Published: SpringerOpen 2019-10-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Radiolabelling
Fluorine-18
Aryl stannanes
Aryl boronic acids
Copper-mediated
Azeotropic drying-free
Online Access:http://link.springer.com/article/10.1186/s41181-019-0079-y

Internet

http://link.springer.com/article/10.1186/s41181-019-0079-y

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