Structural brain signatures of frailty, defined as accumulation of self-reported health deficits in older adults

BackgroundFrailty in older adults has been associated with reduced brain health. However, structural brain signatures of frailty remain understudied. Our aims were: (1) Explore associations between a frailty index (FI) and brain structure on magnetic resonance imaging (MRI). (2) Identify the most im...

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Bibliographic Details
Main Authors: Raquel Gutiérrez-Zúñiga, James R. C. Davis, Kathy Ruddy, Céline De Looze, Daniel Carey, James Meaney, Rose Anne Kenny, Silvin Paul Knight, Roman Romero-Ortuno
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1065191/full