Gut-kidney axis in IgA nephropathy: Role on mesangial cell metabolism and inflammation

Gut-kidney axis in IgA nephropathy: Role on mesangial cell metabolism and inflammation

IgA Nephropathy (IgAN) is the commonest primary glomerular disease around the world and represents a significant cause of end-stage renal disease. IgAN is characterized by mesangial deposition of IgA-immune complexes and mesangial expansion. The pathophysiological process includes an abnormally glyc...

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Bibliographic Details
Main Authors: Mateus Justi Luvizotto, Luísa Menezes-Silva, Viktoria Woronik, Renato C. Monteiro, Niels Olsen Saraiva Câmara
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
IgA nephropathy
kidney
mesangial cells
gut-kidney axis
microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.993716/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.993716/full

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