A phenome-wide association study (PheWAS) to identify the health impacts of 4-cresol sulfate in the Nagahama Study

Abstract Gut-microbiota derived metabolites are important regulators of host biology and metabolism. To understand the impacts of the microbial metabolite 4-cresol sulfate (4-CS) on four chronic diseases [type 2 diabetes mellitus, metabolic syndrome (MetS), non-alcoholic fatty liver disease, and chr...

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Bibliographic Details
Main Authors: Huiting Ou, Shuji Kawaguchi, Kazuhiro Sonomura, Takahisa Kawaguchi, Seri Kitada, Satoshi Yoshiji, François Brial, Dominique Gauguier, Jianguo Xia, Fumihiko Matsuda
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40697-2