Long-lived unipotent Blimp1-positive luminal stem cells drive mammary gland organogenesis throughout adult life

The role of stem/progenitor cell populations in mammary gland morphogenesis is not well understood. Here, the authors show that a transcriptional repressor, Blimp1, is expressed in a rare luminal stem cell population, which contribute to duct formation, and survive multiple rounds of pregnancy and i...

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Bibliographic Details
Main Authors: Salah Elias, Marc A. Morgan, Elizabeth K. Bikoff, Elizabeth J. Robertson
Format: Article
Language:English
Published: Nature Portfolio 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01971-w