Generation of novel in vitro flexible kidney organoid model to investigate the role of extracellular vesicles in induction of nephrogenesis

Generation of novel in vitro flexible kidney organoid model to investigate the role of extracellular vesicles in induction of nephrogenesis

Abstract Background During kidney organogenesis, metanephric mesenchyme (MM) and ureteric bud (UB) interact reciprocally to form nephrons. Signaling stimuli involved in these interactions include Wnts, growth factors and nano/micro particles. How UB and MM are interacting is not completely understoo...

Full description

Bibliographic Details
Main Authors: Naveed Ahmad, Anatoliy Samoylenko, Ichrak Abene, Eslam Abdelrady, Artem Zhyvolozhnyi, Olha Makieieva, Geneviève Bart, Ilya Skovorodkin, Seppo J Vainio
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cell Communication and Signaling
Subjects:
Nephrogenesis
UB
MM
Wnt
EVs
UB cell line
Online Access:https://doi.org/10.1186/s12964-023-01374-z

Internet

https://doi.org/10.1186/s12964-023-01374-z

Similar Items