The Presynaptic v-ATPase Reversibly Disassembles and Thereby Modulates Exocytosis but Is Not Part of the Fusion Machinery

The Presynaptic v-ATPase Reversibly Disassembles and Thereby Modulates Exocytosis but Is Not Part of the Fusion Machinery

Vacuolar H+-ATPase (v-ATPase) is a multi-subunit complex comprising two domains: the cytosolic V1 domain catalyzing ATP hydrolysis and the membranous V0 sector translocating protons across membranes. In addition to proton pumping, a direct function of the V0 proteolipid ring in membrane fusion has b...

Full description

Bibliographic Details
Main Authors: Anna Bodzęta, Martin Kahms, Jürgen Klingauf
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Cell Reports
Subjects:
v-ATPase
reversible disassembly
synaptic vesicle recycling
exocytosis
fusion machinery
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717310069

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717310069

Similar Items