Clinical pattern of checkpoint inhibitor-induced liver injury in a multicentre cohort

Clinical pattern of checkpoint inhibitor-induced liver injury in a multicentre cohort

Background & Aims: Immune checkpoint inhibitors (ICIs) have changed the landscape of cancer therapy. Liver toxicity occurs in up to 25% of patients treated with ICIs. The aim of our study was to describe the different clinical patterns of ICI-induced hepatitis and to assess their outcome. Me...

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Main Authors: Lina Hountondji, Christophe Ferreira De Matos, Fanny Lebossé, Xavier Quantin, Candice Lesage, Pascale Palassin, Valérian Rivet, Stéphanie Faure, Georges-Philippe Pageaux, Éric Assenat, Laurent Alric, Amel Zahhaf, Dominique Larrey, Philine Witkowski Durand Viel, Benjamin Riviere, Selves Janick, Stéphane Dalle, Alexandre Thibault Jacques Maria, Thibaut Comont, Lucy Meunier
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:JHEP Reports
Subjects:
Immune checkpoint inhibitors
Immune-related adverse events
Drug-induced liver injury
Cancer
Hepatitis
Cholangitis
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923000502

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http://www.sciencedirect.com/science/article/pii/S2589555923000502

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