Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7

Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7

Summary: In the conventional model of transcriptional activation, transcription factors bind to response elements and recruit co-factors, including histone acetyltransferases. Contrary to this model, we show that the histone acetyltransferase KAT7 (HBO1/MYST2) is required genome wide for histone H3...

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Bibliographic Details
Main Authors: Andrew J. Kueh, Maria I. Bergamasco, Anna Quaglieri, Belinda Phipson, Connie S.N. Li-Wai-Suen, Ingrid M. Lönnstedt, Yifang Hu, Zhi-Ping Feng, Chris Woodruff, Rose E. May, Stephen Wilcox, Alexandra L. Garnham, Michael P. Snyder, Gordon K. Smyth, Terence P. Speed, Tim Thomas, Anne K. Voss
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
CP: Stem cell research
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722018848

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http://www.sciencedirect.com/science/article/pii/S2211124722018848

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