Chemokine signals are crucial for enhanced homing and differentiation of circulating osteoclast progenitor cells

Chemokine signals are crucial for enhanced homing and differentiation of circulating osteoclast progenitor cells

Abstract Background The peripheral blood (PB) monocyte pool contains osteoclast progenitors (OCPs), which contribute to osteoresorption in inflammatory arthritides and are influenced by the cytokine and chemokine milieu. We aimed to define the importance of chemokine signals for migration and activa...

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Bibliographic Details
Main Authors: Alan Sucur, Zrinka Jajic, Marinko Artukovic, Marina Ikic Matijasevic, Branimir Anic, Darja Flegar, Antonio Markotic, Tomislav Kelava, Sanja Ivcevic, Natasa Kovacic, Vedran Katavic, Danka Grcevic
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Arthritis Research & Therapy
Subjects:
Osteoclast progenitor cells
Chemokines
Chemokine receptors
Osteoclasts
Rheumatoid arthritis
Peripheral blood
Online Access:http://link.springer.com/article/10.1186/s13075-017-1337-6

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http://link.springer.com/article/10.1186/s13075-017-1337-6

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