Single-Cell RNA Sequencing Reveals Differences in Chromatin Remodeling and Energy Metabolism among In Vivo-Developed, In Vitro-Fertilized, and Parthenogenetically Activated Embryos from the Oocyte to 8-Cell Stages in Pigs

In vitro-fertilized (IVF) and parthenogenetically activated (PA) embryos, key to genetic engineering, face more developmental challenges than in vivo-developed embryos (IVV). We analyzed single-cell RNA-seq data from the oocyte to eight-cell stages in IVV, IVF, and PA porcine embryos, focusing on de...

Full description

Bibliographic Details
Main Authors: Jianlin Fan, Chang Liu, Yunjing Zhao, Qianqian Xu, Zhi Yin, Zhonghua Liu, Yanshuang Mu
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/14/3/465