Late effects of high-dose methotrexate treatment in childhood cancer survivors—a systematic review

Abstract Background High-dose methotrexate (HD-MTX) is used in the treatment of different childhood cancers, including leukemia, the most common cancer type and is commonly defined as an intravenous dose of at least 1 g/m2 body surface area per application. A systematic review on late effects on dif...

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Bibliographic Details
Main Authors: Eveline Daetwyler, Mario Bargetzi, Maria Otth, Katrin Scheinemann
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-09145-0