Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment

Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment

Background/aims: Changes in gene expression profiles among individuals with inflammatory bowel diseases (IBDs) could potentially influence the responsiveness to anti-TNF treatment. The aim of this study was to identify genes that could serve as predictors of early response to anti-TNF therapies in p...

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Main Authors: Sara Salvador-Martín, Gianluca Rubbini, Perceval Vellosillo, Paula Zapata-Cobo, Marta Velasco, Laura M. Palomino, Susana Clemente, Oscar Segarra, Ana Moreno-Álvarez, Ana Fernández-Lorenzo, Begoña Pérez-Moneo, Montserrat Montraveta, Cesar Sánchez, Mar Tolín, Inés Loverdos, María José Fobelo, Victor Manuel Navas-López, Lorena Magallares, Ruth García-Romero, Ricardo Torres-Peral, Alejandro Rodríguez, Ferrán Bossacoma, Vicente Merino-Bohórquez, Enrique Salcedo, Rebeca Álvarez, Ana Dopazo, María Sanjurjo-Sáez, Luis A. López-Fernández
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
RNA-seq
Pharmacogenomics
Inflammatory bowel disease
Anti-TNF drugs
Pediatrics
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222400180X

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http://www.sciencedirect.com/science/article/pii/S075333222400180X

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