Molecular etiology of atherogenesis--in vitro induction of lipidosis in macrophages with a new LDL model.

Molecular etiology of atherogenesis--in vitro induction of lipidosis in macrophages with a new LDL model.

BACKGROUND: Atherosclerosis starts by lipid accumulation in the arterial intima and progresses into a chronic vascular inflammatory disease. A major atherogenic process is the formation of lipid-loaded macrophages in which a breakdown of the endolysomal pathway results in irreversible accumulation o...

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Bibliographic Details
Main Authors: Luis M B B Estronca, Joao C P Silva, Julio L Sampaio, Andrej Shevchenko, Paul Verkade, Alfin D N Vaz, Winchil L C Vaz, Otilia V Vieira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3325953?pdf=render

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http://europepmc.org/articles/PMC3325953?pdf=render

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