Interactions between core histone marks and DNA methyltransferases predict DNA methylation patterns observed in human cells and tissues

DNA methylation and histone modifications are two major epigenetic marks in mammalian cells. Previous studies have revealed that these two mechanisms interact although a quantitative model of these is still lacking in mammalian cells. Here we sought to develop such a model by systematically evaluati...

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Bibliographic Details
Main Authors: Kai Fu, Giancarlo Bonora, Matteo Pellegrini
Format: Article
Language:English
Published: Taylor & Francis Group 2020-03-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2019.1666649