Tramadol Treatment Induces Change in Phospho-Cyclic Adenosine Monophosphate Response Element-Binding Protein and Delta and Mu Opioid Receptors within Hippocampus and Amygdala Areas of Rat Brain

Background: Tramadol induces its unique effects through opioid pathways, but the exact mechanism is not known. The study aims to evaluate changes in the level of mu-opioid receptor (μOR), delta-opioid receptor (δOR), and phosphorylated cyclic adenosine monophosphate (cAMP) response element-binding p...

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Bibliographic Details
Main Authors: Hamid Ahmadian-Moghadam, Mitra Sadat Sadat-Shirazi, Somaiyeh Azmoun, Reza Vafadoost, Solmaz Khalifeh, Mohammad Reza Zarrindast
Format: Article
Language:English
Published: Kerman University of Medical Sciences 2021-08-01
Series:Addiction and Health
Online Access:https://ahj.kmu.ac.ir/article_91756_8a501e32b14117fa0629a1ebcfeb9a95.pdf