NOX1 and PRDX6 synergistically support migration and invasiveness of hepatocellular carcinoma cells through enhanced NADPH oxidase activity

NOX1 and PRDX6 synergistically support migration and invasiveness of hepatocellular carcinoma cells through enhanced NADPH oxidase activity

The NADPH oxidase 1 (NOX1) complex formed by proteins NOX1, p22phox, NOXO1, NOXA1, and RAC1 plays an important role in the generation of superoxide and other reactive oxygen species (ROS) which are involved in normal and pathological cell functions due to their effects on diverse cell signaling path...

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Bibliographic Details
Main Authors: Daniel J. Lagal, J. Antonio Bárcena, Raquel Requejo-Aguilar, C. Alicia Padilla, Thomas L. Leto
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Advances in Redox Research
Subjects:
NOX1
NADPH oxidase 1
PRDX6
Superoxide
Mesenchymal phenotype
Cancer progression
Online Access:http://www.sciencedirect.com/science/article/pii/S2667137923000206

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http://www.sciencedirect.com/science/article/pii/S2667137923000206

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