The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome.

The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome.

Chronic hepatitis B is a global health problem and current treatments only suppress hepatitis B virus (HBV) infection, highlighting the need for new curative treatments. Oxygen levels influence HBV replication and we previously reported that hypoxia inducible factors (HIFs) activate the basal core p...

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Bibliographic Details
Main Authors: Senko Tsukuda, James M Harris, Andrea Magri, Peter Balfe, Aleem Siddiqui, Peter A C Wing, Jane A McKeating
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011917&type=printable

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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011917&type=printable

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