Synthesis, Molecular Docking, and Biofilm Formation Inhibitory Activity of Bis(Indolyl)Pyridines Analogues of the Marine Alkaloid Nortopsentin

Synthesis, Molecular Docking, and Biofilm Formation Inhibitory Activity of Bis(Indolyl)Pyridines Analogues of the Marine Alkaloid Nortopsentin

An efficient and simple protocol for the synthesis of a new class of diverse bis(indolyl)pyridines analogues of the marine alkaloid nortopsentin has been reported. A one-pot four-component condensation of 3-cyanocarbomethylindole, various aldehyde, 3-acetylindole, and ammonium acetate in glacial ace...

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Bibliographic Details
Main Authors: Heba M. Abo-Salem, Hayam A. Abd El Salam, Anhar Abdel-Aziem, Mohamed S. Abdel-Aziz, Eslam Reda El-Sawy
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
nortopsentin
bis(indolyl)pyridine
benzofuran
antimicrobial
biofilm formation
molecular docking
Online Access:https://www.mdpi.com/1420-3049/26/14/4112

Internet

https://www.mdpi.com/1420-3049/26/14/4112

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