Using the PfEMP1 head structure binding motif to deal a blow at severe malaria.

Plasmodium falciparum (Pf) malaria causes 200 million cases worldwide, 8 million being severe and complicated leading to ∼1 million deaths and ∼100,000 abortions annually. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) has been implicated in cytoadherence and infected erythrocyte rose...

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Bibliographic Details
Main Authors: Manuel E Patarroyo, Martha Patricia Alba, Hernando Curtidor, Magnolia Vanegas, Hannia Almonacid, Manuel A Patarroyo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3917906?pdf=render