The development of bispecific antibodies and their applications in tumor immune escape

The development of bispecific antibodies and their applications in tumor immune escape

Abstract During the past two decades, a great evolution of bispecific antibodies (BsAbs) for therapeutic applications has been made. BsAbs can bind simultaneously two different antigens or epitopes, which leads to a wide range of applications including redirecting T cells or NK cells to tumor cells,...

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Bibliographic Details
Main Authors: Xiaolong Zhang, Yuanyuan Yang, Dongmei Fan, Dongsheng Xiong
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Experimental Hematology & Oncology
Subjects:
Bispecific antibody
Chemical conjugation
Quadroma
scFv
Cancer immunotherapy
Immune escape
Online Access:http://link.springer.com/article/10.1186/s40164-017-0072-7

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http://link.springer.com/article/10.1186/s40164-017-0072-7

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