Nucleation of cadherin clusters on cell-cell interfaces

Abstract Cadherins mediate cell-cell adhesion and help the cell determine its shape and function. Here we study collective cadherin organization and interactions within cell-cell contact areas, and find the cadherin density at which a ‘gas-liquid’ phase transition occurs, when cadherin monomers begi...

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Bibliographic Details
Main Authors: Neil Ibata, Eugene M. Terentjev
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23220-x