Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

Ribosomal RNAs, the most abundant cellular RNA species, have evolved as the structural scaffold and the catalytic center of protein synthesis in every living organism. In eukaryotes, they are produced from a long primary transcript through an intricate sequence of processing steps that include RNA c...

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Bibliographic Details
Main Authors: Maxime Aubert, Marie-Françoise O’Donohue, Simon Lebaron, Pierre-Emmanuel Gleizes
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/8/4/123