Chemodivergent transformations of amides using gem-diborylalkanes as pro-nucleophiles

Amides are versatile synthetic building blocks, however the general stability of the amide bond makes its selective transformation challenging. Here, the authors report a chemodivergent transformation of primary, secondary and tertiary amides by using 1,1-diborylalkanes as pro-nucleophiles.

Bibliographic Details
Main Authors: Wei Sun, Lu Wang, Yue Hu, Xudong Wu, Chungu Xia, Chao Liu
Format: Article
Language:English
Published: Nature Portfolio 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16948-5