Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells

Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells

Macrophages play pivotal roles in host defense and immune homeostasis, which have two major functional polarization states, the classically activated M1 and the alternatively activated M2. Interleukin (IL)-17A is an immune modulator able to shape macrophage phenotypes. Wnt/β-catenin is a development...

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Bibliographic Details
Main Authors: Chao Yuan, Dandan Yang, Jia Ma, Jiali Yang, Jing Xue, Fuyang Song, Xiaoming Liu
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2020-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Wnt/β-catenin signaling
Interleukin-17A
Macrophage polarization
STAT
Immune regulation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000800604&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000800604&tlng=en

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