Intracerebral gadolinium deposition following blood–brain barrier disturbance in two different mouse models

Abstract To evaluate the influence of the blood–brain barrier on neuronal gadolinium deposition in a mouse model after multiple intravenous applications of the linear contrast agent gadodiamide. The prospective study held 54 mice divided into three groups: healthy mice (A), mice with iatrogenic indu...

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Bibliographic Details
Main Authors: M. L. Kromrey, S. Oswald, D. Becher, J. Bartel, J. Schulze, H. Paland, T. Ittermann, S. Hadlich, J. P. Kühn, S. Mouchantat
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36991-8