Quantitative Multiplexed Proteomics Could Assist Therapeutic Decision Making in Non-Small Cell Lung Cancer Patients with Ambiguous ALK Test Results

Quantitative Multiplexed Proteomics Could Assist Therapeutic Decision Making in Non-Small Cell Lung Cancer Patients with Ambiguous ALK Test Results

Therapeutic guidance in non-small cell lung cancer (NSCLC) tumors that are positive for anaplastic lymphoma kinase (<i>ALK</i>) fluorescent in situ hybridization (FISH), but negative for ALK immunohistochemistry, is still challenging. Parallel routine screening of 4588 NSCLC cases identi...

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Bibliographic Details
Main Authors: Ho Jung An, Eunkyung An, Shahrooz Rabizadeh, Wei-Li Liao, Jon Burrows, Todd Hembrough, Jin Hyung Kang, Chan Kwon Park, Tae-Jung Kim
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
ALK
non-small-cell lung cancer
proteomics
selected reaction monitoring
fluorescent in situ hybridization
immunohistochemistry
Online Access:https://www.mdpi.com/2072-6694/13/10/2337

Internet

https://www.mdpi.com/2072-6694/13/10/2337

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