High-dimensional profiling reveals Tc17 cell enrichment in active Crohn’s disease and identifies a potentially targetable signature

High-dimensional profiling reveals Tc17 cell enrichment in active Crohn’s disease and identifies a potentially targetable signature

The T cell compartment in patients with Crohn's disease is dysregulated. Here the authors use cytometric profiling to reveal an enrichment of distinct Tc17 cells during active Crohn's disease and may suggest CD6 as a potential target for therapeutic studies.

Bibliographic Details
Main Authors: A.-M. Globig, A. V. Hipp, P. Otto-Mora, M. Heeg, L. S. Mayer, S. Ehl, H. Schwacha, M. Bewtra, V. Tomov, R. Thimme, P. Hasselblatt, B. Bengsch
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31229-z

Internet

https://doi.org/10.1038/s41467-022-31229-z

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