A single-cell regulatory map of postnatal lung alveologenesis in humans and mice

A single-cell regulatory map of postnatal lung alveologenesis in humans and mice

Summary: Ex-utero regulation of the lungs’ responses to breathing air and continued alveolar development shape adult respiratory health. Applying single-cell transposome hypersensitive site sequencing (scTHS-seq) to over 80,000 cells, we assembled the first regulatory atlas of postnatal human and mo...

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Bibliographic Details
Main Authors: Thu Elizabeth Duong, Yan Wu, Brandon Chin Sos, Weixiu Dong, Siddharth Limaye, Lauraine H. Rivier, Greg Myers, James S. Hagood, Kun Zhang
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Cell Genomics
Subjects:
lung development
alveolus
chromatin accessibility
transcriptional regulation
human cell atlas
mouse cell atlas
Online Access:http://www.sciencedirect.com/science/article/pii/S2666979X22000283

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http://www.sciencedirect.com/science/article/pii/S2666979X22000283

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