Modeling human early otic sensory cell development with induced pluripotent stem cells.

The inner ear represents a promising system to develop cell-based therapies from human induced pluripotent stem cells (hiPSCs). In the developing ear, Notch signaling plays multiple roles in otic region specification and for cell fate determination. Optimizing hiPSC induction for the generation of a...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Hanae Lahlou, Alejandra Lopez-Juarez, Arnaud Fontbonne, Emmanuel Nivet, Azel Zine
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Public Library of Science (PLoS) 2018-01-01
Σειρά:PLoS ONE
Διαθέσιμο Online:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198954/1/pone.0198954.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210218%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210218T134433Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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