DNA Hypomethylation in the TNF-Alpha Gene Predicts Rheumatoid Arthritis Classification in Patients with Early Inflammatory Symptoms

DNA Hypomethylation in the TNF-Alpha Gene Predicts Rheumatoid Arthritis Classification in Patients with Early Inflammatory Symptoms

Biomarkers for the classification of rheumatoid arthritis (RA), and particularly for anti-citrullinated peptide antibody (ACPA)-negative patients, remain an important hurdle for the early initiation of treatment. Taking advantage of DNA-methylation patterns specific to early RA, quantitative methyla...

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Bibliographic Details
Main Authors: Rujiraporn Pitaksalee, Rekha Parmar, Richard Hodgett, Paul Emery, Frederique Ponchel
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
DNA-methylation
qMSP biomarker
rheumatoid arthritis
Online Access:https://www.mdpi.com/2073-4409/12/19/2376

Internet

https://www.mdpi.com/2073-4409/12/19/2376

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