Computational estimation of quality and clinical relevance of cancer cell lines

Abstract Immortal cancer cell lines (CCLs) are the most widely used system for investigating cancer biology and for the preclinical development of oncology therapies. Pharmacogenomic and genome‐wide editing screenings have facilitated the discovery of clinically relevant gene–drug interactions and n...

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Bibliographic Details
Main Authors: Lucia Trastulla, Javad Noorbakhsh, Francisca Vazquez, James McFarland, Francesco Iorio
Format: Article
Language:English
Published: Springer Nature 2022-07-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.202211017